This Osteo Bi-Flex Glucosamine Chondroitin Triple StrengthΔ formula with 50mcg of Vitamin D includes Joint Shield 5-LOXIN Advanced**, a clinically studied herbal extract that has been shown to significantly improve joint comfort in 7 days.*† This Osteo Bi-Flex joint supplement formula also includes Vitamin D to help support immune and bone health.* Glucosamine chondroitin, an ingredient essential for the maintenance of joint cartilage and comfortable joint movement provides additional joint support to nourish and strengthen your joints for the long term.* Osteo Bi-Flex is the #1 pharmacist-recommended *** joint care supplement brand, built on quality and innovation. With a focus on providing high-quality joint supplements that fulfill a variety of needs, Osteo Bi-Flex is a trusted brand, committed to providing products to support joint comfort, mobility and flexibility* so you can keep moving, the way you were made to.